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 | Seeking natural colors for foods and beverages |
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PepsiCo is evaluating different natural color ingredients and technologies to replace Yellow #5, Yellow #6, Red #40, and Blue #1 for multiple food and beverage brands in order to address consumer demand. Specific challenges are in the Red #40 (food) and Blue #1 (food & beverage) replacers. |
| | Seeking technologies to reduce GHGs in all aspects of the supply chain and manufacturing process. |
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PepsiCo is committed to reducing GHG emissions from seed to shelf. We are looking to engage with partners who can assist us in our goal of reducing GHG 20% by 2030 and achieving net-zero emissions by 2050. As new technologies emerge, efficiencies will be gained and PepsiCo aims to remain at the forefront of best practices in the food and beverage industry. PepsiCo is seeking technologies to reduce GHGs in all aspects of the supply chain and manufacturing process. Solutions may be in one or more of the following areas: • Agriculture – sustainable farming and the reduction of GHG intensive fertilizers • Manufacturing – adopting energy efficient manufacturing processes; novel methods for utilizing waste; use of renewable thermal energy at scale • Packaging – alternative packaging materials and formats that reduce GHGs • Distribution – technologies to assist in the efficiency of our company-owned and third party fleet |
 | Seeking existing market solutions targeted towards crawling insects |
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The issue of crawling insects in homes has been an ongoing issue. The popular types of crawling insects causing problems have been ants and cockroaches. The search will focus on existing market solutions targeted towards crawling insects such as ants and cockroaches (other types of crawling insects are in scope i.e., bed bugs). |
 | DRooTES: Double Rooted Trailing Edge Serrations for quiet blades |
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Aerofoil blade designs with double rooted serrations that reduce trailing edge noise to the maximum through destructive interference. They can be attached to existing blades so are particularly suitable for retrofitting to larger blades, such as wind turbines. They are however applicable to a wide range of blades moving in air and water, for example turbines, fans, rotary wings and fixed wings. The scale of application ranges from small drones (small blades operating at high speeds) to large wind turbines (large blades operating at slower speeds). |
 | NanoMEDIC gene editing delivery system |
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Background Gene therapy holds great potential for the treatment of genetic diseases. However, delivery to specific tissues is still a major bottleneck. Although AAV-delivered CRISPR-Cas9 editing is being developed for multiple diseases, its therapeutic translation is hindered by the limited packaging capacity of viral particles and possible immune response to them. Moreover, AAV transgenes tend to be expressed for an extended period of time, which increases off-target mutagenesis risk. Extracellular vesicles (EV) is another option and, when combined with ribonucleoprotein (RNP) delivery of CRISPR-Cas9, reduces off-target effects. The structural polyprotein Gag is typically used to package cargo into EVs, which nevertheless limits the EV packaging capacity. The present invention is an all-in-one EV delivery system termed NanoMEDIC (nanomembrane-derived extracellular vesicles for the delivery of macromolecular cargo). It is a transient EV-based CRISPR-Cas9 editing delivery system which ensures efficient genome editing in various cell types. |
 | A new generation of substrates to culture microorganisms |
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Bac3Gel develops and distributes advanced substrates to harness the full power of microorganisms. Bac3Gel substrates are the first that combine three-dimensionality with gradients of oxygen, nutrients and physical properties to allow the growth of complex microbial communities and currently unculturable bacteria that depend on these microenvironments to thrive. Bac3Gel substrates aim to revolutionise the status quo of microbiology to unlock innovative bacteria-based solutions to solve challenges across multiple bio-based applications. Our mission is to provide a new standard for microbial culture to ultimately foster the discovery of new antibiotics and bio-based solutions to feed the ever-growing demand for bio-based innovative treatments, as well as the development of microbiome-modulating drugs to address 90% of diseases linked to human microbiome dysbiosis. If you are looking for a new solution to culture your microorganisms or looking to culture unculturable microorganisms contact us: contact@bac3gel.com |
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